5umv
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Crystal structure of the BRCT domain of S. cerevisiae Rev1
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Structural highlights
FunctionREV1_YEAST Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.[1] [2] [3] See AlsoReferences
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This page was last modified 13:30, 4 October 2023.