5v54

Crystal structure of 5-HT1B receptor in complex with methiothepin

spinqualitylabelsall models 5v54, resolution 3.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5v54 is a 2 chain structure with sequence from Homo sapiens and Spodoptera frugiperda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.9Å Ligands: 89F Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function 5HT1B_HUMAN This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. See Also 5-hydroxytryptamine receptor 3D structures

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