5vfk

Solution structure of an archaeal DUF61 family protein SSO0941

spinqualitylabelsall models 5vfk Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5vfk is a 1 chain structure with sequence from Saccharolobus solfataricus P2. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q97ZH2_SACS2 Publication Abstract from PubMed Domain of unknown function 61 (DUF61) family proteins widely exist in archaea and the genes of DUF61 proteins in crenarchaea are in an operon containing two genes of box C/D RNA protein complexes. Here we report the solution NMR structure of DUF61 family member protein SSO0941, from the hyperthermophilic archaeon Sulfolobus solfataricus. SSO0941 has a rigid core structure and flexible N- and C-terminal regions as well as a negatively-charged independent C-terminal helix. The core structure consists of N- and C-terminal subdomains, in which the C-terminal subdomain shows significant structural similarity with several nucleic acid binding proteins. The structure of SSO0941 is the first representative structure of DUF61 family proteins. Solution structure of an archaeal DUF61 family protein SSO0941 encoded by a gene in the operon of box C/D RNA protein complexes.,Zhou T, Yao X, Wang J, Feng Y J Struct Biol. 2018 Mar 8. pii: S1047-8477(18)30065-0. doi:, 10.1016/j.jsb.2018.03.003. PMID:29526782 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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