5wce
From Proteopedia
Jump to navigationJump to search
Caulobacter crescentus pol III beta
| ||||||||||||
Structural highlights
FunctionDPO3B_CAUVC Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[UniProtKB:P0A988] See AlsoContents | ||||||||||||||||||
This page was last modified 14:10, 4 October 2023.