5x1i
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Vanillate/3-O-methylgallate O-demethylase, LigM, substrate free form
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Structural highlights
FunctionLIGM_SPHSK Involved in the catabolism of vanillate and syringate. Catalyzes the transfer of a methyl moiety from vanillate or 3-O-methylgallate (3MGA) to tetrahydrofolate, forming protocatechuate (PCA) or gallate, respectively, and methyl-tetrahydrofolate. Has similar activities with both substrates (PubMed:15743951). Cannot use syringate (PubMed:15743951). Uses an ordered, sequential kinetic mechanism (PubMed:28373573).[1] [2] References
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This page was last modified 09:19, 20 March 2024.