5xnb

Crystal structure of the IcmS-IcmW-DotL complex of the Legionella type IVb secretion system

spinqualitylabelsall models 5xnb, resolution 2.59Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5xnb is a 18 chain structure with sequence from Legionella pneumophila. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.594Å Ligands: BTB Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DOTL_LEGPH Component of the Dot/Icm type IVB secretion system (T4BSS), which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:17040490, PubMed:22694730, PubMed:32513920). Part of a subcomplex which recruits effector proteins and delivers them to the core transmembrane subcomplex (PubMed:23028312, PubMed:32513920). Plays a central role in the assembly of the subcomplex (PubMed:32513920). Required for the recruitment of IcmS and IcmW to the inner membrane and for the translocation of adapter-dependent substrates (PubMed:23028312). May have ATPase activity (Probable).

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