5y6p

Structure of the phycobilisome from the red alga Griffithsia pacifica

Loading... Status: waiting for Mol* initialization Structural highlights 5y6p is a 48 chain structure with sequence from Griffithsia pacifica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.5Å Ligands: CYC, PEB, PUB, PVN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Life on Earth depends on photosynthesis for its conversion of solar energy to chemical energy. Photosynthetic organisms have developed a variety of light-harvesting systems to capture sunlight. The largest light-harvesting complex is the phycobilisome (PBS), the main light-harvesting antenna in cyanobacteria and red algae. It is composed of phycobiliproteins and linker proteins but the assembly mechanisms and energy transfer pathways of the PBS are not well understood. Here we report the structure of a 16.8-megadalton PBS from a red alga at 3.5 A resolution obtained by single-particle cryo-electron microscopy. We modelled 862 protein subunits, including 4 linkers in the core, 16 rod-core linkers and 52 rod linkers, and located a total of 2,048 chromophores. This structure reveals the mechanisms underlying specific interactions between linkers and phycobiliproteins, and the formation of linker skeletons. These results provide a firm structural basis for our understanding of complex assembly and the mechanisms of energy transfer within the PBS. Structure of phycobilisome from the red alga Griffithsia pacifica.,Zhang J, Ma J, Liu D, Qin S, Sun S, Zhao J, Sui SF Nature. 2017 Nov 2;551(7678):57-63. doi: 10.1038/nature24278. Epub 2017 Oct 18. PMID:29045394 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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