5yf1
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Crystal structure of CARNMT1 bound to carnosine and SFG
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Structural highlights
FunctionCARME_HUMAN N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).[1] References
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This page was last modified 10:23, 27 March 2024.