6b11
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TylHI in complex with native substrate 23-deoxy-5-O-mycaminosyl-tylonolide (23-DMTL)
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Structural highlights
FunctionTYLH1_STRFR Involved in the biosynthesis of the complex macrolide antibiotic tylosin. Catalyzes the hydroxylation of 20-oxo-5-O-beta-mycaminosyltylactone at the C-23 position to yield 5-O-beta-mycaminosyltylonolide.[1] References | ||||||||||||||||||||
This page was last modified 14:30, 4 October 2023.