6bly

Cryo-EM structure of human CPSF-160-WDR33 complex at 3.36A resolution

Loading... Status: waiting for Mol* initialization Structural highlights 6bly is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.36Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CPSF1_HUMAN Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.

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