6cxm

Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218

spinqualitylabelsall models 6cxm, resolution 2.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6cxm is a 2 chain structure with sequence from Mycolicibacterium smegmatis MC2 155. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.65Å Ligands: MMV, NAP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function I7FC10_MYCS2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194] See Also Dihydrofolate reductase 3D structures

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