6d0a
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Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution
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Structural highlights
FunctionAADAT_HUMAN Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).[1] See AlsoReferences
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This page was last modified 15:14, 4 October 2023.