6e0l

Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase with Apcpp and Upnpp

spinqualitylabelsall models 6e0l, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6e0l is a 1 chain structure with sequence from Rhodothermus marinus SG0.5JP17-172. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.25Å Ligands: 2KH, APC, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CDNE_RHOMG CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type I-B(UU) CBASS system (PubMed:32839535). Cyclic dinucleotide synthase that catalyzes the synthesis of 3'3'-cyclic UMP-AMP (cUMP-AMP) from UTP and ATP, a second messenger for cell signal transduction.

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