6e0t
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C-terminal domain of Fission Yeast OFD1
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Structural highlights
FunctionOFD1_SCHPO Prolyl 3,4-dihydroxylase that catalyzes 3,4-dihydroxylation of 'Pro-62' of small ribosomal subunit uS12 (rps23 and rps2302), thereby regulating protein translation termination efficiency. Negative regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which is released from the membrane and enters the nucleus to activate hypoxic gene expression.[1] [2] References
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This page was last modified 14:38, 13 March 2024.