6edj
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Cryo-EM structure of Woodchuck hepatitis virus capsid
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Structural highlights
FunctionHBEAG_WHV1 May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.[HAMAP-Rule:MF_04076] Contents | ||||||||||||||
This page was last modified 14:40, 13 March 2024.