6ee1 | pdb_00006ee1

Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA

spinqualitylabelsall models 6ee1, resolution 2.36Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ee1 is a 4 chain structure with sequence from Mycobacterium tuberculosis CDC1551. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.36Å Ligands: ACO, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ACEA2_MYCTO Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

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