6f4v

Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution

spinqualitylabelsall models 6f4v, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6f4v is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.8Å Ligands: CL, EDO, GOL, NA, Z9K, Z9L Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function KAIN_HUMAN Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. See Also Serpin 3D structures

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