6fdk

Structure of Chlamydia trachomatis effector protein Cdu1 bound to ubiquitin

spinqualitylabelsall models 6fdk, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6fdk is a 2 chain structure with sequence from Chlamydia trachomatis 434/Bu and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.6Å Ligands: AYE, CL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CDUB1_CHLT2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease possesses deubiquitinating and deneddylating activities (By similarity). Impairs ubiquitination and degradation of NF-kappa-B inhibitor alpha (NFKBIA), thereby preventing NF-kappa-B activation. See Also 3D structures of ubiquitin

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