| Structural highlights
Function
CSEP4_BLUG1 Secreted effector that increases susceptibility to infection in both monocotyledonous and dicotyledonous plants (PubMed:23441578, PubMed:30856238). Non-catalytic homolog of fungal RNases that binds host RNA and inhibits the degradation of host ribosomal RNA induced by ribosome-inactivating proteins (RIPs), preventing host cell death, an inviable interaction and demise of the fungus (PubMed:30856238).[1] [2]
References
- ↑ Pliego C, Nowara D, Bonciani G, Gheorghe DM, Xu R, Surana P, Whigham E, Nettleton D, Bogdanove AJ, Wise RP, Schweizer P, Bindschedler LV, Spanu PD. Host-induced gene silencing in barley powdery mildew reveals a class of ribonuclease-like effectors. Mol Plant Microbe Interact. 2013 Jun;26(6):633-42. PMID:23441578 doi:10.1094/MPMI-01-13-0005-R
- ↑ Pennington HG, Jones R, Kwon S, Bonciani G, Thieron H, Chandler T, Luong P, Morgan SN, Przydacz M, Bozkurt T, Bowden S, Craze M, Wallington EJ, Garnett J, Kwaaitaal M, Panstruga R, Cota E, Spanu PD. The fungal ribonuclease-like effector protein CSEP0064/BEC1054 represses plant immunity and interferes with degradation of host ribosomal RNA. PLoS Pathog. 2019 Mar 11;15(3):e1007620. PMID:30856238 doi:10.1371/journal.ppat.1007620
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