6fzt

Crystal structure of Smad8_9-MH1 bound to the GGCGC site.

spinqualitylabelsall models 6fzt, resolution 2.46Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6fzt is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL, ZN Gene: SMAD9, MADH6, MADH9, SMAD8 (HUMAN) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [SMAD9_HUMAN] Heritable pulmonary arterial hypertension. The disease may be caused by mutations affecting the gene represented in this entry. Function [SMAD9_HUMAN] Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).

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