6ikm

Crystal structure of SpuE-Spermidine in complex with ScFv5

spinqualitylabelsall models 6ikm, resolution 3.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ikm is a 36 chain structure with sequence from Homo sapiens and Pseudomonas aeruginosa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.398Å Ligands: SO4, SPD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function SPUE_PSEAE Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence. See Also Antibody 3D structures

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