6j6w

Mutant K23N of heat shock factor 4-DBD

spinqualitylabelsall models 6j6w, resolution 1.69Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6j6w is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.693Å Ligands: NA, NO3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease HSF4_HUMAN Early-onset lamellar cataract;Total early-onset cataract. The disease is caused by mutations affecting the gene represented in this entry. Function HSF4_HUMAN DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription. See Also Heat shock factor

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