Structural highlights
Function
PTP1_ARATH Protein-tyrosine-phosphatase that dephosphorylates and probably inhibits MPK6 in non-oxidative stress conditions. In association with MKP1, represses salicylic acid (SA) and camalexin biosynthesis, thus modulating defense response. May also repress MPK3. Dephosphorylates and inactivates MPK4 in vitro.[1] [2] [3] [4]
References
- ↑ Huang Y, Li H, Gupta R, Morris PC, Luan S, Kieber JJ. ATMPK4, an Arabidopsis homolog of mitogen-activated protein kinase, is activated in vitro by AtMEK1 through threonine phosphorylation. Plant Physiol. 2000 Apr;122(4):1301-10. PMID:10759527 doi:10.1104/pp.122.4.1301
- ↑ Gupta R, Luan S. Redox control of protein tyrosine phosphatases and mitogen-activated protein kinases in plants. Plant Physiol. 2003 Jul;132(3):1149-52. PMID:12857797 doi:10.1104/pp.103.020792
- ↑ Bartels S, Anderson JC, González Besteiro MA, Carreri A, Hirt H, Buchala A, Métraux JP, Peck SC, Ulm R. MAP kinase phosphatase1 and protein tyrosine phosphatase1 are repressors of salicylic acid synthesis and SNC1-mediated responses in Arabidopsis. Plant Cell. 2009 Sep;21(9):2884-97. PMID:19789277 doi:10.1105/tpc.109.067678
- ↑ Xu Q, Fu HH, Gupta R, Luan S. Molecular characterization of a tyrosine-specific protein phosphatase encoded by a stress-responsive gene in Arabidopsis. Plant Cell. 1998 May;10(5):849-57. PMID:9596642 doi:10.1105/tpc.10.5.849
