6lxu

Crystal structure of methionine gamma-lyase from Fusobacterium nucleatum

spinqualitylabelsall models 6lxu, resolution 1.19Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6lxu is a 1 chain structure with sequence from Fusobacterium nucleatum subsp. nucleatum ATCC 25586. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.19Å Ligands: LLP, MPD, NO3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MEGL_FUSNN Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia, and that of L-homocysteine (By similarity). Can also use L-cysteine as substrate, catalyzing its alpha,beta-elimination; this activity seems to only minimally contribute to the production of hydrogen sulfide (H2S) by F.nucleatum in the oral cavity, which is toxic for a large variety of cells in periodontal regions (PubMed:21798982).[UniProtKB:Q8L0X4] See Also Methionine gamma-lyase 3D structures

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