6m3f
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Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P212121
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Structural highlights
FunctionNUCG_MOUSE Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity). See AlsoContents | ||||||||||||||||||||
This page was last modified 10:48, 27 March 2024.