6mst

Cryo-EM structure of human AA amyloid fibril

Loading... Status: waiting for Mol* initialization Structural highlights 6mst is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.7Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SAA1_HUMAN Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. Function SAA1_HUMAN Major acute phase reactant. Apolipoprotein of the HDL complex.

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