6ne0

Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14)

Loading... Status: waiting for Mol* initialization Structural highlights 6ne0 is a 12 chain structure with sequence from Pseudomonas aeruginosa UCBPP-PA14. This structure supersedes the now removed PDB entry 6mpu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.4Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CSY1_PSEAB CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 and Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). Involved in crRNA production or stability. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity. See Also Endonuclease 3D structures

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