6nep

Structure of human PACRG-MEIG1 complex

spinqualitylabelsall models 6nep, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6nep is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.097625Å Ligands: CL, PHI, PO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PACRG_HUMAN Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.

Proteopedia Page Contributors and Editors (what is this?)

OCA