6nfa

Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity

spinqualitylabelsall models 6nfa, resolution 2.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6nfa is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.7Å Ligands: 9K1, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function VAV_HUMAN Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

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