6nrd

hTRiC-hPFD Class4

Loading... Status: waiting for Mol* initialization Structural highlights 6nrd is a 14 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 8.2Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TCPE_HUMAN Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry. Function TCPE_HUMAN Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. See Also Chaperonin 3D structures

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