6pe6

PANK3 complex structure with compound PZ-3022

spinqualitylabelsall models 6pe6, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6pe6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.6Å Ligands: ANP, MG, ODG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PANK3_HUMAN Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity). Publication Abstract from PubMed [Figure: see text]. Pantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia.,Subramanian C, Frank MW, Tangallapally R, Yun MK, Edwards A, White SW, Lee RE, Rock CO, Jackowski S Sci Transl Med. 2021 Sep 15;13(611):eabf5965. doi: 10.1126/scitranslmed.abf5965. , Epub 2021 Sep 15. PMID:34524863 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Pantothenate kinase 3D structures

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