6pk4

cryoEM structure of the substrate-bound human CTP synthase 2 filament

Loading... Status: waiting for Mol* initialization Structural highlights 6pk4 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.5Å Ligands: ATP, UTP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PYRG2_HUMAN Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.

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