6plf

Crystal structure of human PHGDH complexed with Compound 1

spinqualitylabelsall models 6plf, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6plf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.7Å Ligands: EDO, ONV Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SERA_HUMAN Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815. It is characterized by congenital microcephaly, psychomotor retardation, and seizures. Function SERA_HUMAN See Also Phosphoglycerate dehydrogenase

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