6pnw

X-RAY STRUCTURE OF ERABUTOXIN C, A DIMERIC NEUROTOXIN

spinqualitylabelsall models 6pnw, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6pnw is a 2 chain structure with sequence from Laticauda semifasciata. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function 3S1EC_LATSE Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission. Binds to Torpedo marmorata nAChR (Kd=0.14 nM) (PubMed:7721859).

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