6q3r

ASPERGILLUS ACULEATUS GALACTANASE

spinqualitylabelsall models 6q3r, resolution 2.69Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6q3r is a 2 chain structure with sequence from Aspergillus aculeatus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.69Å Ligands: ACT, BMA, CA, EDO, GAL, NAG, PEG, PG4, PG6, PGE, PRD_900113 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GANA_ASPAC Publication Abstract from PubMed beta-1,4-Galactanases are glycoside hydrolases that are involved in the degradation of pectin and belong to family 53 in the classification of glycoside hydrolases. Previous studies have elucidated the structures of several fungal and two bacterial galactanases, while biochemical studies have indicated differences in the product profiles of different members of the family. Structural studies of ligand complexes have to date been limited to the bacterial members of the family. Here, the first structure of a fungal galactanase in complex with a disaccharide is presented. Galactobiose binds to subsites -1 and -2, thus improving our understanding of ligand binding to galactanases. Structure of Aspergillus aculeatus beta-1,4-galactanase in complex with galactobiose.,Torpenholt S, Poulsen JCN, Muderspach SJ, De Maria L, Lo Leggio L Acta Crystallogr F Struct Biol Commun. 2019 Jun 1;75(Pt 6):399-404. doi:, 10.1107/S2053230X19005612. Epub 2019 May 10. PMID:31204685 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Beta-1%2C4-galactanase

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