6qtc
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tSH2 domain of transcription elongation factor Spt6 complexed with tyrosine phosphorylated CTD
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Structural highlights
FunctionSPT6_CANGA Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity). See AlsoContents | ||||||||||||||||||||
This page was last modified 10:41, 15 November 2023.