6tx1
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Structural highlights
FunctionHPF1_NEMVE Cofactor for serine ADP-ribosylation that confers serine specificity on PARP. Switches the amino acid specificity of PARP from aspartate or glutamate to serine residues. Acts by completing the active site of PARP: forms a composite active site composed of residues from HPF1 and PARP.[UniProtKB:Q9NWY4] Contents | ||||||||||||||||||
This page was last modified 07:38, 1 May 2024.