6w1d
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Structure of human mitochondrial complex Nfs1-ISCU2 (WT)-ISD11 with E.coli ACP1 at 1.8 A resolution (NIAU)2
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Structural highlights
DiseaseNFS1_HUMAN Severe neonatal lactic acidosis due to NFS1-ISD11 complex deficiency. FunctionNFS1_HUMAN Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.[1] See AlsoReferences
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This page was last modified 14:14, 18 October 2023.