6wj3
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CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state
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Structural highlights
FunctionRRAGC_HUMAN Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.[1] See AlsoReferences
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This page was last modified 14:44, 6 March 2024.