6xxr

ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDEA-NH2

spinqualitylabelsall models 6xxr, resolution 1.48Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6xxr is a 4 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.48Å Ligands: 2L5, 2TL, ACY, NO3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ENAH_HUMAN Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity).

Proteopedia Page Contributors and Editors (what is this?)

OCA