6z4u
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X-ray Crystallographic Structure of Orf9b from SARS-CoV-2
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Structural highlights
FunctionORF9B_SARS2 Plays a role in inhibiting the host innate immune response by targeting the mitochondrial-associated innate immune response. Acts by binding to host TOMM70, inhibiting its binding to HSP90AB1 thereby disrupting the interferon activation pathway.[1] [2] References
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This page was last modified 13:41, 24 January 2024.