7bln

VPS35/VPS29 arch of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins

spinqualitylabelsall models 7bln, resolution 8.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7bln is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 8.9Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function VPS29_HUMAN Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). See Also Vacuolar protein sorting-associated protein 3D structures

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