7clr

CryoEM structure of S.typhimurium flagellar LP ring

spinqualitylabelsall models 7clr, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7clr is a 52 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.5Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function FLGI_SALTY Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. Publication Abstract from PubMed The basal body of the bacterial flagellum is a rotary motor that consists of several rings (C, MS and LP) and a rod. The LP ring acts as a bushing supporting the distal rod for its rapid and stable rotation without much friction. Here, we use electron cryomicroscopy to describe the LP ring structure around the rod, at 3.5 A resolution, from Salmonella Typhimurium. The structure shows 26-fold rotational symmetry and intricate intersubunit interactions of each subunit with up to six partners, which explains the structural stability. The inner surface is charged both positively and negatively. Positive charges on the P ring (the part of the LP ring that is embedded within the peptidoglycan layer) presumably play important roles in its initial assembly around the rod with a negatively charged surface. Structure of the molecular bushing of the bacterial flagellar motor.,Yamaguchi T, Makino F, Miyata T, Minamino T, Kato T, Namba K Nat Commun. 2021 Jul 22;12(1):4469. doi: 10.1038/s41467-021-24715-3. PMID:34294704 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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