7jk8

EmrE S64V mutant bound to tetra(4-fluorophenyl)phosphonium at pH 5.8

spinqualitylabelsall models 7jk8 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7jk8 is a 2 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solid-state NMR Ligands: VCJ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function EMRE_ECOLI Multidrug transporter that expels positively charged hydrophobic drugs across the inner membrane of E.coli., thereby conferring resistance to a wide range of toxic compounds. The drug efflux is coupled to an influx of protons. Is involved in the resistance of E.coli cells to methyl viologen, ethidium bromide and acriflavine. Is also able to transport tetraphenylphosphonium (TPP(+)) and benzalkonium.

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