7ko7

Structure of the native cardiac thin filament at pCa=5.8 having upper Tn in Ca2+ free state and lower Tn in Ca2+ bound state

spinqualitylabelsall models 7ko7, resolution 8.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7ko7 is a 29 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 8.3Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TNNC1_PIG Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. See Also Actin 3D structures Tropomyosin 3D structures Troponin 3D structures

Proteopedia Page Contributors and Editors (what is this?)

OCA