7kps
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Structure of a GNAT superfamily PA3944 acetyltransferase in complex with AcCoA
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Structural highlights
FunctionATSE3_PSEAE Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers the peptide Asp-Phe methyl ester (or aspartame) and the peptide antibiotics polymyxin B and colistin. Other substrates like dopamine, serotonin, puromycin, chloramphenicol, D-glucosamine, glycine and N-alpha-acetyl-L-glutamine are used and displayed lower activity.[1] References
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This page was last modified 06:53, 9 August 2023.