7lv9

Marseillevirus heterotrimeric (hexameric) nucleosome

spinqualitylabelsall models 7lv9, resolution 4.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7lv9 is a 8 chain structure with sequence from Marseillevirus marseillevirus and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.5Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function D2XB48_GBMV Publication Abstract from PubMed Certain large DNA viruses, including those in the Marseilleviridae family, encode histones. Here we show that fused histone pairs Hbeta-Halpha and Hdelta-Hgamma from Marseillevirus are structurally analogous to the eukaryotic histone pairs H2B-H2A and H4-H3. These viral histones form 'forced' heterodimers, and a heterotetramer of four such heterodimers assembles DNA to form structures virtually identical to canonical eukaryotic nucleosomes. The structure of a virus-encoded nucleosome.,Valencia-Sanchez MI, Abini-Agbomson S, Wang M, Lee R, Vasilyev N, Zhang J, De Ioannes P, La Scola B, Talbert P, Henikoff S, Nudler E, Erives A, Armache KJ Nat Struct Mol Biol. 2021 May;28(5):413-417. doi: 10.1038/s41594-021-00585-7. , Epub 2021 Apr 29. PMID:33927388 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Histone 3D structures

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