7o4d

QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline

spinqualitylabelsall models 7o4d, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7o4d is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.249Å Ligands: FAD, SO4, V1Z, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NQO2_HUMAN The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

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