7ods

State B of the human mitoribosomal large subunit assembly intermediate

spinqualitylabelsall models 7ods, resolution 3.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7ods is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.1Å Ligands: AYA, FES, K, MG, N, OMU, PM8, SAC, SAM, THC, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MASU1_HUMAN May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. See Also Ribosome 3D structures

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