7pz1

Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH8535

spinqualitylabelsall models 7pz1, resolution 2.45Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7pz1 is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.45Å Ligands: 8HA, EDO, GOL, NI Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function OGG1_MOUSE DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. See Also DNA glycosylase 3D structures

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